Title : Downregulation of the inflammatory network in senescent fibroblasts and aging tissues of the long-lived and cancer-resistant subterranean wild rodent, Spalax.

Pub. Date : 2020 Jan

PMID : 31605433






1 Functional Relationships(s)
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1 Spalax fibroblasts undergo replicative senescence (RS) and etoposide-induced senescence (EIS), evidenced by an increased activity of senescence-associated beta-galactosidase (SA-beta-Gal), growth arrest, and overexpression of p21, p16, and p53 mRNAs. Etoposide tumor protein p53 Homo sapiens