Pub. Date : 2019 Oct 1
PMID : 31593984
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Methods: The effect of curcumin on interleukin (IL)-1beta induced-proinflammatory cytokine production was determined using quantitative real-time PCR, enzyme-linked immunosorbent assay (ELISA), and Western blot analysis. | Curcumin | interleukin 1 alpha | Homo sapiens |
| 2 | Results: Treatment with curcumin resulted in a dose- and time-dependent decrease in IL-1beta-induced synthesis of inflammatory cytokines, including IL-6, IL-8, MCP-1, and ICAM-1 at both mRNA and protein levels. | Curcumin | interleukin 1 alpha | Homo sapiens |
| 3 | Curcumin significantly suppressed IL-1beta-induced phosphorylated extracellular signal-regulated kinase, Akt, c-Jun NH(2)-terminal kinase, and nuclear factor kappa-light-chain-enhancer of activated B cells, p65 proteins and stimulated beta-catenin translocation into nucleus during adipogenesis. | Curcumin | interleukin 1 alpha | Homo sapiens |