Pub. Date : 2019 Oct
PMID : 31591827
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Along with insulin, beta-cells co-secrete the neurotransmitter ATP which acts as a positive autocrine signal via P2Y1 receptors to activate phospholipase C and increase the production of diacylglycerol (DAG). | Adenosine Triphosphate | insulin | Homo sapiens |
| 2 | Since DAG activates protein kinase D1 (PKD1) to potentiate glucose-stimulated insulin release, we hypothesized that autocrine ATP signaling activates downstream PKD1 to regulate insulin secretion. | Adenosine Triphosphate | insulin | Homo sapiens |
| 3 | Since DAG activates protein kinase D1 (PKD1) to potentiate glucose-stimulated insulin release, we hypothesized that autocrine ATP signaling activates downstream PKD1 to regulate insulin secretion. | Adenosine Triphosphate | insulin | Homo sapiens |