Title : The Effect of Polyphenols on Hypercholesterolemia through Inhibiting the Transport and Expression of Niemann-Pick C1-Like 1.

Pub. Date : 2019 Oct 6

PMID : 31590417






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Luteolin reduced the binding of Sterol-regulatory element-binding protein 2 (SREBP2) in the promoter region of the NPC1L1 gene and decreased mRNA levels of SREBP2 and hepatocyte nuclear factor 4alpha. Luteolin sterol regulatory element binding transcription factor 2 Homo sapiens
2 Luteolin reduced the binding of Sterol-regulatory element-binding protein 2 (SREBP2) in the promoter region of the NPC1L1 gene and decreased mRNA levels of SREBP2 and hepatocyte nuclear factor 4alpha. Luteolin sterol regulatory element binding transcription factor 2 Homo sapiens
3 Luteolin reduced the binding of Sterol-regulatory element-binding protein 2 (SREBP2) in the promoter region of the NPC1L1 gene and decreased mRNA levels of SREBP2 and hepatocyte nuclear factor 4alpha. Luteolin sterol regulatory element binding transcription factor 2 Homo sapiens