Title : Simvastatin preparations promote PDGF-BB secretion to repair LPS-induced endothelial injury through the PDGFRβ/PI3K/Akt/IQGAP1 signalling pathway.

Pub. Date : 2019 Dec

PMID : 31576676






4 Functional Relationships(s)
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Protein Name
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1 Simvastatin preparations promote PDGF-BB secretion to repair LPS-induced endothelial injury through the PDGFRbeta/PI3K/Akt/IQGAP1 signalling pathway. Simvastatin AKT serine/threonine kinase 1 Homo sapiens
2 SV/SV-NPs promoted the secretion of platelet-derived growth factor-BB (PDGF-BB) and activated the PDGFRbeta/PI3K/Akt/IQGAP1 pathway. Simvastatin AKT serine/threonine kinase 1 Homo sapiens
3 SV/SV-NPs promoted the secretion of platelet-derived growth factor-BB (PDGF-BB) and activated the PDGFRbeta/PI3K/Akt/IQGAP1 pathway. Simvastatin AKT serine/threonine kinase 1 Homo sapiens
4 SV preparations restored endothelial barrier function by restoring endothelial cell migration, which is involved in the regulation of the PDGFRbeta/PI3K/Akt/IQGAP1 pathway and PDGF-BB secretion. Simvastatin AKT serine/threonine kinase 1 Homo sapiens