Pub. Date : 2019 Dec
PMID : 31576676
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Simvastatin preparations promote PDGF-BB secretion to repair LPS-induced endothelial injury through the PDGFRbeta/PI3K/Akt/IQGAP1 signalling pathway. | Simvastatin | AKT serine/threonine kinase 1 | Homo sapiens |
2 | SV/SV-NPs promoted the secretion of platelet-derived growth factor-BB (PDGF-BB) and activated the PDGFRbeta/PI3K/Akt/IQGAP1 pathway. | Simvastatin | AKT serine/threonine kinase 1 | Homo sapiens |
3 | SV/SV-NPs promoted the secretion of platelet-derived growth factor-BB (PDGF-BB) and activated the PDGFRbeta/PI3K/Akt/IQGAP1 pathway. | Simvastatin | AKT serine/threonine kinase 1 | Homo sapiens |
4 | SV preparations restored endothelial barrier function by restoring endothelial cell migration, which is involved in the regulation of the PDGFRbeta/PI3K/Akt/IQGAP1 pathway and PDGF-BB secretion. | Simvastatin | AKT serine/threonine kinase 1 | Homo sapiens |