Pub. Date : 2019 Sep 26
PMID : 31561560
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In fetal testes, the RA-degrading enzyme CYP26B1 prevents meiosis initiation. | Tretinoin | cytochrome P450, family 26, subfamily b, polypeptide 1 | Mus musculus |
| 2 | Collectively, our data reveal that CYP26B1 has other activities apart from metabolizing RA in fetal gonads and suggest a role of endogenous RA in amplifying Stra8, rather than being the initial inducer of Stra8. | Tretinoin | cytochrome P450, family 26, subfamily b, polypeptide 1 | Mus musculus |
| 3 | Collectively, our data reveal that CYP26B1 has other activities apart from metabolizing RA in fetal gonads and suggest a role of endogenous RA in amplifying Stra8, rather than being the initial inducer of Stra8. | Tretinoin | cytochrome P450, family 26, subfamily b, polypeptide 1 | Mus musculus |