Title : Discovery of new small molecule inhibitors targeting isocitrate dehydrogenase 1 (IDH1) with blood-brain barrier penetration.

Pub. Date : 2019 Dec 1

PMID : 31561044






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Isocitrate dehydrogenase 1 (IDH1), which catalyzes the conversion of isocitrate to alpha-ketoglutarate, is one of key enzymes in the tricarboxylic acid cycle (TCA). isocitric acid isocitrate dehydrogenase 1 (NADP+), soluble Mus musculus
2 Isocitrate dehydrogenase 1 (IDH1), which catalyzes the conversion of isocitrate to alpha-ketoglutarate, is one of key enzymes in the tricarboxylic acid cycle (TCA). isocitric acid isocitrate dehydrogenase 1 (NADP+), soluble Mus musculus