Pub. Date : 2020
PMID : 31561038
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regulation of CFTR Bicarbonate Channel Activity by WNK1: Implications for Pancreatitis and CFTR-related disorders. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 2 | Regulation of CFTR Bicarbonate Channel Activity by WNK1: Implications for Pancreatitis and CFTR-related disorders. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 3 | BACKGRAOUD & AIMS: Aberrant epithelial bicarbonate (HCO3-) secretion caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene is associated with several diseases including cystic fibrosis and pancreatitis. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 4 | BACKGRAOUD & AIMS: Aberrant epithelial bicarbonate (HCO3-) secretion caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene is associated with several diseases including cystic fibrosis and pancreatitis. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 5 | RESULTS: Among the WNK1, SPAK, and OSR1 kinases that constitute a [Cl-]i-sensitive kinase cascade, the expression of WNK1 alone was sufficient to increase the CFTR bicarbonate permeability (PHCO3/PCl) and conductance (GHCO3) in patch clamp recordings. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |