Pub. Date : 2019 Oct
PMID : 31556692
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NUDT15 and TPMT Genetic Polymorphisms Are Related to Azathioprine Intolerance in Chinese Patients with Rheumatic Diseases. | Azathioprine | nudix hydrolase 15 | Homo sapiens |
| 2 | Results: The TPMT*3C and NUDT15*3 genotypes were significantly associated with AZA-induced leukopenia (p = 0.007 and 4.475 x 10-6, respectively). | Azathioprine | nudix hydrolase 15 | Homo sapiens |
| 3 | Conclusion: This study demonstrated that NUDT15*3 and TPMT*3C are both highly predictive genetic markers for AZA-induced toxicity in Chinese populations with rheumatic diseases. | Azathioprine | nudix hydrolase 15 | Homo sapiens |