Title : ERK1/2-HNF4α axis is involved in epigallocatechin-3-gallate inhibition of HBV replication.

Pub. Date : 2020 Feb

PMID : 31554961






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1 Furthermore, we showed that EGCG treatment dose-dependently decreased the expression of hepatocyte nuclear factor 4alpha (HNF4alpha) both at the mRNA and protein levels, which could be reversed by pretreatment with the ERK1/2 inhibitor PD98059 (20 muM). 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one mitogen-activated protein kinase 3 Homo sapiens