Title : MUC1-C Activates the NuRD Complex to Drive Dedifferentiation of Triple-Negative Breast Cancer Cells.

Pub. Date : 2019 Nov 15

PMID : 31519689






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 MUC1-C/MYC complexes selectively activated the MTA1 and MBD3 genes and posttranscriptionally induced CHD4 expression in basal- but not luminal-type BC cells. Phenobarbital mucin 1, cell surface associated Homo sapiens
2 Targeting MUC1-C and these NuRD components also induced expression of FOXA1, GATA3, and other markers associated with the luminal phenotype. Phenobarbital mucin 1, cell surface associated Homo sapiens