Title : Suppression of Nuclear Factor-κB by Glucocorticoid Receptor Blocks Estrogen-Induced Apoptosis in Estrogen-Deprived Breast Cancer Cells.

Pub. Date : 2019 Oct

PMID : 31511352






2 Functional Relationships(s)
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1 Here, we demonstrated that E2 widely activated adipose inflammatory factors such as fatty acid desaturase 1 (FADS1), IL6, and TNFalpha in LTED breast cancer cells. Estradiol interleukin 6 Homo sapiens
2 Furthermore, dexamethasone was synergistic or additive with E2 in upregulating FADS1 and IL6 expression, whereas it selectively and constantly suppressed TNFalpha expression induced by E2 in LTED breast cancer cells. Estradiol interleukin 6 Homo sapiens