Title : Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban.

Pub. Date : 2019 Nov

PMID : 31506301






2 Functional Relationships(s)
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1 Notably, transporter-mediated DDI simulations between rivaroxaban and P-gp inhibitors (verapamil and ketoconazole) yielded minimal increases in rivaroxaban"s systemic exposure when P-gp-mediated efflux was solely inhibited. Verapamil ATP binding cassette subfamily B member 1 Homo sapiens
2 Notably, transporter-mediated DDI simulations between rivaroxaban and P-gp inhibitors (verapamil and ketoconazole) yielded minimal increases in rivaroxaban"s systemic exposure when P-gp-mediated efflux was solely inhibited. Verapamil ATP binding cassette subfamily B member 1 Homo sapiens