Title : CLEFMA Activates the Extrinsic and Intrinsic Apoptotic Processes through JNK1/2 and p38 Pathways in Human Osteosarcoma Cells.

Pub. Date : 2019 Sep 9

PMID : 31505816






1 Functional Relationships(s)
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1 Using inhibitors of JNK (JNK-in-8) and p38 (SB203580), CLEFMA"s increases of cleaved caspases 3, 8, and 9 could be expectedly suppressed, but they could not be affected by co-treatment with the ERK inhibitor (U0126). SB 203580 mitogen-activated protein kinase 1 Homo sapiens