Pub. Date : 2019 Sep
PMID : 31502574
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Meanwhile a western blot assay showed that c-Met together with matrix metalloproteinases-9 (MMP9) and phosphorylation of the serine/threonine kinase AKT (p-AKT) was significantly down-regulated by calycosin. | 7,3'-dihydroxy-4'-methoxyisoflavone | matrix metallopeptidase 9 | Homo sapiens |
| 2 | Meanwhile a western blot assay showed that c-Met together with matrix metalloproteinases-9 (MMP9) and phosphorylation of the serine/threonine kinase AKT (p-AKT) was significantly down-regulated by calycosin. | 7,3'-dihydroxy-4'-methoxyisoflavone | matrix metallopeptidase 9 | Homo sapiens |
| 3 | Additionally, the expression levels of c-Met, MMP9 and p-AKT were inhibited by calycosin in c-Met overexpressed cells. | 7,3'-dihydroxy-4'-methoxyisoflavone | matrix metallopeptidase 9 | Homo sapiens |
| 4 | These data collectively indicated that calycosin possibility targeting on c-Met and exert an anti-tumor role via MMP9 and AKT. | 7,3'-dihydroxy-4'-methoxyisoflavone | matrix metallopeptidase 9 | Homo sapiens |