Title : Quercetin protects against cisplatin-induced acute kidney injury by inhibiting Mincle/Syk/NF-κB signaling maintained macrophage inflammation.

Pub. Date : 2020 Jan

PMID : 31497913






2 Functional Relationships(s)
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1 The results demonstrated that quercetin can significantly inhibit expression and secretion of IL-1beta, IL-6, and TNF-alpha in LPS-induced bone marrow-derived macrophages (BMDMs) and reduce activity of Mincle/Syk/NF-kappaB signaling in vitro. Quercetin interleukin 6 Homo sapiens
2 We also found that quercetin can strongly reduce the concentration of serum creatinine, BUN, IL-1beta, IL-6, and TNF-alpha in cisplatin-induced AKI model. Quercetin interleukin 6 Homo sapiens