Pub. Date : 2019 Sep
PMID : 31492557
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effect of PLA2G4A downstream signaling, including Cyclooxygenase 2, Prostaglandin E2(PGE2) and Signal transducer and activator of transcription 3(STAT3), on EMT and metastasis was further detected with in vitro and in vivo experiments. | Dinoprostone | phospholipase A2 group IVA | Homo sapiens |
| 2 | ANXA10 promoted the progression of PHCCA and facilitated metastasis by promoting the EMT process via the PLA2G4A/PGE2/STAT3 pathway. | Dinoprostone | phospholipase A2 group IVA | Homo sapiens |
| 3 | ANXA10, PLA2G4A and their downstream molecules, such as COX2 and PGE2, may be promising drug targets of PHCCA and DCCA. | Dinoprostone | phospholipase A2 group IVA | Homo sapiens |