Title : p53 prevents doxorubicin cardiotoxicity independently of its prototypical tumor suppressor activities.

Pub. Date : 2019 Sep 24

PMID : 31488712






1 Functional Relationships(s)
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1 Given a similar mtDNA protection role of p53 in doxorubicin-treated human induced pluripotent stem cell (iPSC)-derived cardiomyocytes, the mitochondrial markers associated with cardiomyopathy development observed in blood and skeletal muscle cells may have prognostic utility. Doxorubicin tumor protein p53 Homo sapiens