Title : Lethal toxicities after capecitabine intake in a previously 5-FU-treated patient: why dose matters with dihydropryimidine dehydrogenase deficiency.

Pub. Date : 2019 Aug

PMID : 31486738






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 DPD phenotyping (i.e., uracil plasma levels >250 ng/ml, dihydrouracil/uracil ratio <0.5) confirmed that this patient was profoundly DPD deficient. Uracil dihydropyrimidine dehydrogenase Homo sapiens
2 DPD phenotyping (i.e., uracil plasma levels >250 ng/ml, dihydrouracil/uracil ratio <0.5) confirmed that this patient was profoundly DPD deficient. Uracil dihydropyrimidine dehydrogenase Homo sapiens