Title : Decreased SLC26A3 expression and function in intestinal epithelial cells in response to Cryptosporidium parvum infection.

Pub. Date : 2019 Dec 1

PMID : 31483700






3 Functional Relationships(s)
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1 We and others have previously shown impaired chloride absorption in infectious diarrhea due to dysregulation of SLC26A3 [downregulated in adenoma (DRA)], the human intestinal apical membrane Cl-/HCO3- exchanger protein. Chlorides solute carrier family 26 member 3 Homo sapiens
2 We and others have previously shown impaired chloride absorption in infectious diarrhea due to dysregulation of SLC26A3 [downregulated in adenoma (DRA)], the human intestinal apical membrane Cl-/HCO3- exchanger protein. Chlorides solute carrier family 26 member 3 Homo sapiens
3 Our results suggest that impaired chloride absorption due to downregulation of DRA could be one of the contributing factors to CP-induced acute, self-limiting diarrhea in immunocompetent hosts. Chlorides solute carrier family 26 member 3 Homo sapiens