Title : Prolactin response to sodium valproate in schizophrenics with and without tardive dyskinesia.

Pub. Date : 1988

PMID : 3148149






3 Functional Relationships(s)
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1 Prolactin response to sodium valproate in schizophrenics with and without tardive dyskinesia. Valproic Acid prolactin Homo sapiens
2 Sodium valproate decreased plasma prolactin levels in healthy subjects (P less than 0.001) and in schizophrenic patients with TD (P less than 0.001), but not in chronic schizophrenics without TD. Valproic Acid prolactin Homo sapiens
3 Although the neural or biochemical substrate underlying the different responses of plasma prolactin to sodium valproate in schizophrenics with and without TD remains unclear, these results provide the first neuroendocrine evidence able to differentiate dyskinetic subjects from those without TD within a schizophrenic population. Valproic Acid prolactin Homo sapiens