Title : DMPK is a New Candidate Mediator of Tumor Suppressor p53-Dependent Cell Death.

Pub. Date : 2019 Sep 1

PMID : 31480541






2 Functional Relationships(s)
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1 We found that, in response to DNA-damaging agent doxorubicin, expression of myotonic dystrophy protein kinase (DMPK), which is known to upregulate actomyosin contraction, was increased in a p53-dependent manner. Doxorubicin tumor protein p53 Homo sapiens
2 Furthermore, we found that doxorubicin treatment induced p73 expression, which was significantly attenuated by downregulation of p53. Doxorubicin tumor protein p53 Homo sapiens