Title : UV increases skin-derived 1α,25-dihydroxyvitamin D3 production, leading to MMP-1 expression by altering the balance of vitamin D and cholesterol synthesis from 7-dehydrocholesterol.

Pub. Date : 2019 Dec

PMID : 31470109






1 Functional Relationships(s)
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Protein Name
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1 Keratinocytes express both 25-hydroxylase (CYP27A1 and CYP2R1) and 1alpha-hydroxylase (CYP27B1), critical enzymes involved in active vitamin D synthesis. Vitamin D cytochrome P450 family 2 subfamily R member 1 Homo sapiens