Title : Fangchinoline, a Bisbenzylisoquinoline Alkaloid can Modulate Cytokine-Impelled Apoptosis via the Dual Regulation of NF-κB and AP-1 Pathways.

Pub. Date : 2019 Aug 28

PMID : 31466313






1 Functional Relationships(s)
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1 FCN attenuated growth of both leukemic and multiple myeloma cells and repressed NF-kappaB, and AP-1 activation through diverse mechanisms, including attenuation of phosphorylation of IkappaB kinase (IKK) and p65. fangchinoline RELA proto-oncogene, NF-kB subunit Homo sapiens