Pub. Date : 2019
PMID : 31453782
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: Cytochrome P450 2A6 enzyme (CYP2A6), an essential hepatic enzyme involved in the metabolism of drugs, is responsible for a major metabolic pathway of nicotine. | Nicotine | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
| 2 | BACKGROUND: Cytochrome P450 2A6 enzyme (CYP2A6), an essential hepatic enzyme involved in the metabolism of drugs, is responsible for a major metabolic pathway of nicotine. | Nicotine | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
| 3 | Variation in the activity of polymorphic CYP2A6 alleles has been implicated in inter-individual differences in nicotine metabolism. | Nicotine | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |