Title : Platelet-type von Willebrand disease: Local disorder of the platelet GPIbα β-switch drives high-affinity binding to von Willebrand factor.

Pub. Date : 2019 Dec

PMID : 31448872






1 Functional Relationships(s)
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1 Hydrogen-exchange is corroborated by differential scanning calorimetry, which confirms that these mutations destabilize GPIbalpha by allowing the beta-switch to dissociate from the leucine-rich-repeat (LRR) domain. Leucine glycoprotein Ib platelet subunit alpha Homo sapiens