Title : Myeloperoxidase-mediated oxidation of edaravone produces an apparent non-toxic free radical metabolite and modulates hydrogen peroxide-mediated cytotoxicity in HL-60 cells.

Pub. Date : 2019 Nov 1

PMID : 31445206






1 Functional Relationships(s)
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1 Interestingly, the MPO-mediated production of toxic hypochlorous acid exhibited a concentration-dependent biphasic effect, with the apparent optimal edaravone concentration at 10 muM. Hypochlorous Acid myeloperoxidase Homo sapiens