Title : The development of 2-acetylphenol-donepezil hybrids as multifunctional agents for the treatment of Alzheimer's disease.

Pub. Date : 2019 Oct 1

PMID : 31444085






1 Functional Relationships(s)
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1 Therefore, the structure-active-relationship of 2-acetylphenol-donepezil hybrids could encourage the development of multifunction agents with selective AChE inhibition or selective MAO-B inhibition for the treatment of Alzheimer"s disease. 2'-Hydroxyacetophenone acetylcholinesterase (Cartwright blood group) Homo sapiens