Title : Perioperative combined administration of tranexamic acid and dexamethasone in total knee arthroplasty-benefit versus harm?

Pub. Date : 2019 Aug

PMID : 31441836






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1 CONCLUSION: The combined administration of TXA + Dexa significantly reduced the level of postoperative CRP and IL-6, relieve postoperative pain, ameliorate the incidence of POVN, provide additional analgesic and antiemetic effects, reduce postoperative fatigue, and improve ROM, without increasing the risk of complications in primary TKA. Dexamethasone interleukin 6 Homo sapiens