Title : Structure-function relationship of an Urokinase Receptor-derived peptide which inhibits the Formyl Peptide Receptor type 1 activity.

Pub. Date : 2019 Aug 21

PMID : 31434916






1 Functional Relationships(s)
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1 We generated the Ac-(D)-Tyr-(D)-Arg-Aib-(D)-Arg-NH2 (RI-3) peptide which inhibits the uPAR/FPR1 interaction, reducing migration of FPR1 expressing cells toward N-formyl-methionyl-leucyl-phenylalanine (fMLF) and Ser-Arg-Ser-Arg-Tyr (SRSRY) peptides. N-Formylmethionine Leucyl-Phenylalanine formyl peptide receptor 1 Homo sapiens