Pub. Date : 2019 Aug 13
PMID : 31434417
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, potential alterations of mammalian target of rapamycin (mTOR) signaling pathway after treatment with LiCl were checked.Last,LiCl"s efficacy on PTEN null tumors was studied. | Lithium Chloride | mechanistic target of rapamycin kinase | Homo sapiens |
| 2 | Mechanistically, LiCl down-regulated mTOR signaling. | Lithium Chloride | mechanistic target of rapamycin kinase | Homo sapiens |
| 3 | Conclusions: PTEN is the most frequently mutated gene in endometrial carcinoma.By targeting mTOR signaling pathway,LiCl is a promising regimen for the treatment of tumors with PTEN deficiency. | Lithium Chloride | mechanistic target of rapamycin kinase | Homo sapiens |