Pub. Date : 1988 Dec
PMID : 3142887
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | When the alpha DFMO-arrested cells are subsequently incubated during 3 days in a low-serum-containing medium (0.25% FCS), they do not replenish their supply of polyamines, and then continue to express the c-myc gene. | Eflornithine | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 2 | During the subsequent serum deprivation, the alpha DFMO-arrested cells remain "competent" (PDGF-independent), probably as a consequence of their continued expression of c-myc (and possibly other PDGF-inducible genes). | Eflornithine | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |