Title : Type II Epithelial-Mesenchymal Transition Upregulates Protein N-Glycosylation To Maintain Proteostasis and Extracellular Matrix Production.

Pub. Date : 2019 Sep 6

PMID : 31424945






2 Functional Relationships(s)
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1 The mechanism study reveals that the substantial increase in synthesis of ECM proteins in EMT activates the inositol-requiring protein 1 (IRE1alpha)-X-box-binding protein 1 (XBP1) axis of the unfolded protein response (UPR) coupled to the hexosamine biosynthesis pathway (HBP). Hexosamines endoplasmic reticulum to nucleus signaling 1 Homo sapiens
2 The mechanism study reveals that the substantial increase in synthesis of ECM proteins in EMT activates the inositol-requiring protein 1 (IRE1alpha)-X-box-binding protein 1 (XBP1) axis of the unfolded protein response (UPR) coupled to the hexosamine biosynthesis pathway (HBP). Hexosamines endoplasmic reticulum to nucleus signaling 1 Homo sapiens