Pub. Date : 2019 Dec
PMID : 31419517
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The three CYP26 family enzymes, CYP26A1, CYP26B1 and CYP26C1 have all been shown to metabolize all-trans-retinoic acid (atRA) it"s 9-cisRA and 13-cisRA isomers and primary metabolites 4-OH-RA and 4-oxo-RA with high efficiency. | Tretinoin | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 2 | The three CYP26 family enzymes, CYP26A1, CYP26B1 and CYP26C1 have all been shown to metabolize all-trans-retinoic acid (atRA) it"s 9-cisRA and 13-cisRA isomers and primary metabolites 4-OH-RA and 4-oxo-RA with high efficiency. | Tretinoin | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 3 | The three CYP26 family enzymes, CYP26A1, CYP26B1 and CYP26C1 have all been shown to metabolize all-trans-retinoic acid (atRA) it"s 9-cisRA and 13-cisRA isomers and primary metabolites 4-OH-RA and 4-oxo-RA with high efficiency. | Tretinoin | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 4 | The three CYP26 family enzymes, CYP26A1, CYP26B1 and CYP26C1 have all been shown to metabolize all-trans-retinoic acid (atRA) it"s 9-cisRA and 13-cisRA isomers and primary metabolites 4-OH-RA and 4-oxo-RA with high efficiency. | Tretinoin | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 5 | All three CYP26 enzymes are inducible by treatment with atRA in various prenatal and postnatal tissues and cell types. | Tretinoin | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 6 | In humans and in animal models the expression patterns of CYP26 enzymes have been shown to be tissue and cell type specific, and the expression of the CYP26 enzymes is believed to regulate the formation of critical atRA concentration gradients in various tissue types. | Tretinoin | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 7 | In humans and in animal models the expression patterns of CYP26 enzymes have been shown to be tissue and cell type specific, and the expression of the CYP26 enzymes is believed to regulate the formation of critical atRA concentration gradients in various tissue types. | Tretinoin | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |