Title : A fluorescent biosensor-based platform for the discovery of immunogenic cancer cell death inducers.

Pub. Date : 2019

PMID : 31413915






2 Functional Relationships(s)
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1 Thus, certain classes of cytotoxic compounds, for example, anthracyclines, oxaliplatin and taxanes are endowed with the capacity to act on cancer cells to ignite premortem stress pathways that lead to the surface exposure of calreticulin (CALR) and the cellular release of adenosine triphosphate, annexin A1, high mobility group B1 and type-1 interferons. Anthracyclines calreticulin Homo sapiens
2 Thus, certain classes of cytotoxic compounds, for example, anthracyclines, oxaliplatin and taxanes are endowed with the capacity to act on cancer cells to ignite premortem stress pathways that lead to the surface exposure of calreticulin (CALR) and the cellular release of adenosine triphosphate, annexin A1, high mobility group B1 and type-1 interferons. Anthracyclines calreticulin Homo sapiens