Title : Does protein kinase C activation mediate thrombin-induced arachidonate release in human platelets?

Pub. Date : 1988 Oct 28

PMID : 3140902






3 Functional Relationships(s)
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1 Does protein kinase C activation mediate thrombin-induced arachidonate release in human platelets? Arachidonic Acid coagulation factor II, thrombin Homo sapiens
2 The correlation of IP3 production with arachidonate release on increasing the concentrations of thrombin was further examined. Arachidonic Acid coagulation factor II, thrombin Homo sapiens
3 These results suggest that protein kinase C activation may not mediate arachidonate release and that Ca+2 mobilization by IP3 may only partially account for arachidonate release in platelets stimulated with relatively high concentrations of thrombin. Arachidonic Acid coagulation factor II, thrombin Homo sapiens