Title : Quartz Disrupts Iron Homeostasis in Alveolar Macrophages To Impact a Pro-Inflammatory Effect.

Pub. Date : 2019 Sep 16

PMID : 31407890






1 Functional Relationships(s)
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1 Concentrations of interleukin (IL)-1beta, IL-6, IL-8, and tumor necrosis factor-alpha in macrophage supernatant increased following 100 mug/mL silica exposure for 24 h. Treatment of AMs with 500 muM FAC decreased both oxidant generation and cytokine release associated with silica exposure, supporting a dependence of these effects on sequestration of cell metal by the particle surface. Silicon Dioxide C-X-C motif chemokine ligand 8 Homo sapiens