Title : Is the metabolism of alfentanil subject to debrisoquine polymorphism? A study using human liver microsomes.

Pub. Date : 1988 Oct

PMID : 3140691






1 Functional Relationships(s)
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1 The role of a specific cytochrome P-450 form, debrisoquine 4-hydroxylase, in the metabolism of alfentanil was investigated by competitive inhibition experiments over the concentration range 4-100 microM. Alfentanil cytochrome P450 family 4 subfamily F member 3 Homo sapiens