Title : Photoirradiation after aminolevulinic acid treatment suppresses cancer cell proliferation through the HO-1/p21 pathway.

Pub. Date : 2019 Dec

PMID : 31404677






3 Functional Relationships(s)
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1 RESULTS: mRNAs of PAI-1, HO-1, and p21 were upregulated after photoirradiation of HEK293, which was suppressed by N-acetyl-L-cysteine, a reactive oxygen species (ROS) scavenger. Reactive Oxygen Species H3 histone pseudogene 16 Homo sapiens
2 RESULTS: mRNAs of PAI-1, HO-1, and p21 were upregulated after photoirradiation of HEK293, which was suppressed by N-acetyl-L-cysteine, a reactive oxygen species (ROS) scavenger. Reactive Oxygen Species H3 histone pseudogene 16 Homo sapiens
3 CONCLUSION: ALA-PDD or ALA-PDT can result in rapid ROS-induced cell death and may decrease long-term recurrence rates through several pathways including the HO-1/p21 pathway. Reactive Oxygen Species H3 histone pseudogene 16 Homo sapiens