Title : Cardiac glycoside sensitized hepatocellular carcinoma cells to TRAIL via ROS generation, p38MAPK, mitochondrial transition, and autophagy mediation.

Pub. Date : 2019 Nov

PMID : 31392779






1 Functional Relationships(s)
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Protein Name
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1 Caspase activation is dependent on ROS as shown by the ability of CGs to generate ROS and the ROS-N-acetylcysteine (NAC) relationship, which inhibits apoptosis during cotreatment by preventing the formation of caspase-8 and -3. Reactive Oxygen Species caspase 8 Homo sapiens