Pub. Date : 2019
PMID : 31385766
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Association Between CYP3A4 and CYP3A5 Genotypes and Cyclosporine"s Blood Levels and Doses among Jordanian Kidney Transplanted Patients BACKGROUND: Cyclosporine is used as an immunosuppressive agent in kidney transplantation. | Cyclosporine | cytochrome P450 family 3 subfamily A member 5 | Homo sapiens |
| 2 | Cyclosporine is predominantly metabolized by CYP3A4 and CYP3A5. | Cyclosporine | cytochrome P450 family 3 subfamily A member 5 | Homo sapiens |
| 3 | The most commonSingle Nucleotide Polymorphisms (SNPs) affecting cyclosporine metabolism (CYP3A4*1B, CYP3A4*1G,CYP3A4*22 and CYP3A5*3) were investigated among Jordanian kidney transplanted patients to find out the genotypesand allele frequencies of these SNPs. | Cyclosporine | cytochrome P450 family 3 subfamily A member 5 | Homo sapiens |