Title : Transepithelial transport mechanisms of 7,8-dihydroxyflavone, a small molecular TrkB receptor agonist, in human intestinal Caco-2 cells.

Pub. Date : 2019 Aug 1

PMID : 31384856






2 Functional Relationships(s)
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1 We found that breast cancer resistance protein (BCRP) was not involved in 7,8-DHF secretion and that the transport mechanism of 7,8-DHF was passive transport with an active efflux mediated by P-glycoprotein (P-gp) and multidrug resistance associated proteins (MRPs), particularly MRP 2. 6,7-dihydroxyflavone ATP binding cassette subfamily B member 1 Homo sapiens
2 We found that breast cancer resistance protein (BCRP) was not involved in 7,8-DHF secretion and that the transport mechanism of 7,8-DHF was passive transport with an active efflux mediated by P-glycoprotein (P-gp) and multidrug resistance associated proteins (MRPs), particularly MRP 2. 6,7-dihydroxyflavone ATP binding cassette subfamily B member 1 Homo sapiens