Title : Bioavailability and cytosolic kinases modulate response to deoxynucleoside therapy in TK2 deficiency.

Pub. Date : 2019 Aug

PMID : 31383553






1 Functional Relationships(s)
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1 INTERPRETATIONS: These data indicate that the cytosolic pyrimidine salvage pathway enzymes TK1 and dCK are critical for therapeutic efficacy of deoxynucleoside therapy for Tk2 deficiency. pyrimidine Calcium/calmodulin-dependent protein kinase II Drosophila melanogaster