Title : Insulin-dependent phosphorylation of GTP-binding proteins in phospholipid vesicles.

Pub. Date : 1988 Sep 5

PMID : 3137226






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Insulin receptors that have been purified by wheat germ lectin chromatography and either tyrosine-agarose chromatography, sucrose density centrifugation, or insulin-Sepharose chromatography have been co-inserted into phospholipid vesicles with different purified G proteins. Tyrosine insulin Bos taurus
2 Under optimal conditions, about one alpha o- or alpha i-subunit is phosphorylated on a tyrosine residue for every two beta-subunits of the insulin receptor, suggesting a 1:1 interaction between these G proteins and the heterotetrameric (alpha 2 beta 2) insulin receptor molecular. Tyrosine insulin Bos taurus