Title : Interfering cellular lactate homeostasis overcomes Taxol resistance of breast cancer cells through the microRNA-124-mediated lactate transporter (MCT1) inhibition.

Pub. Date : 2019

PMID : 31367191






3 Functional Relationships(s)
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1 Interfering cellular lactate homeostasis overcomes Taxol resistance of breast cancer cells through the microRNA-124-mediated lactate transporter (MCT1) inhibition. Lactic Acid solute carrier family 16 member 1 Homo sapiens
2 Materials and methods: In this study, Human breast cancer cells, BT474, SKBR3 and MCF7 were used to study the causal relationship between the lactate exporter, MCT1 (SLC16A1)-modulated glucose metabolism and Taxol resistance of breast cancer cells. Lactic Acid solute carrier family 16 member 1 Homo sapiens
3 Materials and methods: In this study, Human breast cancer cells, BT474, SKBR3 and MCF7 were used to study the causal relationship between the lactate exporter, MCT1 (SLC16A1)-modulated glucose metabolism and Taxol resistance of breast cancer cells. Lactic Acid solute carrier family 16 member 1 Homo sapiens