Title : The bicarbonate/carbon dioxide pair increases hydrogen peroxide-mediated hyperoxidation of human peroxiredoxin 1.

Pub. Date : 2019 Sep 20

PMID : 31366734






1 Functional Relationships(s)
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Protein Name
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1 Under these conditions, H2O2 oxidizes the sulfenic acid derivative of the Prx peroxidatic Cys (CPSOH) to the sulfinate (CPSO2 -) and sulfonated (CPSO3 -) forms, redirecting the CPSOH intermediate from the catalytic cycle to the hyperoxidation/inactivation pathway. Sulfinate periaxin Homo sapiens