Pub. Date : 2019 Jul 30
PMID : 31366075
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of this study was to estimate the mode of thyroid peroxidase (TPO) inhibition by polyphenols: Chlorogenic acid, rosmarinic acid, quercetin, and rutin. | rosmarinic acid | thyroid peroxidase | Homo sapiens |
| 2 | All the tested polyphenols inhibited TPO; the IC50 values ranged from 0.004 mM to 1.44 mM (for rosmarinic acid and rutin, respectively). | rosmarinic acid | thyroid peroxidase | Homo sapiens |
| 3 | Rutin and rosmarinic acid showed competitive, quercetin-uncompetitive and chlorogenic acid-noncompetitive inhibition effect on TPO. | rosmarinic acid | thyroid peroxidase | Homo sapiens |