Title : BMP-2 gene delivery in cell-loaded and cell-free constructs for bone regeneration.

Pub. Date : 2019

PMID : 31365542






2 Functional Relationships(s)
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1 However, alginate-based gene delivery of BMP-2 to host cells or seeded cells did not result in protein levels adequate for bone formation in this setting, calling for more reliable scaffold compatible transfection methods. Alginates bone morphogenetic protein 2 Rattus norvegicus
2 To induce osteogenicity in bone graft substitutes, plasmid-based expression of BMP-2 (pBMP-2) has been successfully applied in gene activated matrices based on alginate polymer constructs. Alginates bone morphogenetic protein 2 Rattus norvegicus