Title : Recombinant human PRG4 (rhPRG4) suppresses breast cancer cell invasion by inhibiting TGFβ-Hyaluronan-CD44 signalling pathway.

Pub. Date : 2019

PMID : 31361756






3 Functional Relationships(s)
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1 Recombinant human PRG4 (rhPRG4) suppresses breast cancer cell invasion by inhibiting TGFbeta-Hyaluronan-CD44 signalling pathway. Hyaluronic Acid transforming growth factor beta 1 Homo sapiens
2 In mechanistic studies, we find that rhPRG4 suppresses TGFbeta-induced invasiveness of cancer cells by inhibiting the downstream hyaluronan (HA)-cell surface cluster of differentiation 44 (CD44) signalling axis. Hyaluronic Acid transforming growth factor beta 1 Homo sapiens
3 In mechanistic studies, we find that rhPRG4 suppresses TGFbeta-induced invasiveness of cancer cells by inhibiting the downstream hyaluronan (HA)-cell surface cluster of differentiation 44 (CD44) signalling axis. Hyaluronic Acid transforming growth factor beta 1 Homo sapiens