Pub. Date : 2019
PMID : 31359396
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Dysregulation of retinoic acid signaling is implicated in several human cancer types, including melanoma where the gene encoding retinoic acid receptor beta (RARbeta) is frequently silenced by promoter hypermethylation. | Tretinoin | retinoic acid receptor beta | Homo sapiens |
2 | Dysregulation of retinoic acid signaling is implicated in several human cancer types, including melanoma where the gene encoding retinoic acid receptor beta (RARbeta) is frequently silenced by promoter hypermethylation. | Tretinoin | retinoic acid receptor beta | Homo sapiens |
3 | The levels of RARbeta signaling can be modulated using RARbeta agonists (e.g., all-trans retinoic acid) and antagonists (e.g., LE135). | Tretinoin | retinoic acid receptor beta | Homo sapiens |
4 | The levels of RARbeta signaling can be modulated using RARbeta agonists (e.g., all-trans retinoic acid) and antagonists (e.g., LE135). | Tretinoin | retinoic acid receptor beta | Homo sapiens |